Poxviruses (Current Topics in Microbiology & Immunology)

  • 211 Pages
  • 0.73 MB
  • English
Infectious Diseases, Immunology, Microbiology (Specific Aspects), Medical / Nursing, Poxviridae, Poxvirus, Poxvirus., genetics, ram, Science/Mathem
The Physical Object
ID Numbers
Open LibraryOL10153209M
ISBN 100387524304
ISBN 139780387524306

Book Title Poxviruses Editors. Andrew Mercer; Axel Schmidt; Olaf Weber; Series Title Birkhäuser Advances in Infectious Diseases Copyright Publisher Birkhäuser Basel Copyright Holder Springer Basel eBook ISBN DOI / Hardcover ISBN Series ISSN Edition Number 1 Number of Pages XX, Topics.

It includes the latest insights into poxviral molecular biology, diagnosis, therapy, vaccine development and the beneficial exploitation of these viruses in biomedical research.

Each chapter is written by a leader in the field, and the book includes historical perspectives and summaries of recent advances in the : Andrew Mercer. About this book Introduction In contrast to the threat posed by some of these viruses, other poxviruses show exciting beneficial potential including their use as valuable tools in biomedical research and in the delivery of vaccines.

Recombinant Poxviruses provides a comprehensive examination of poxviruses with an emphasis on the potential of these viruses as new vaccines. The book considers a wide range of issues involved in producing new genetically engineered live vaccines, such as efficacy, safety, stability, cost, host range, immune response, immunization route, use of multivalent vaccines, and need for.

Poxviruses may survive for years in dust. Some mammalian poxviruses are considered oncogenic and have been associated with epidermal and fibromatous hyperplasia. Orthopoxvirus Vaccinia Virus This poxvirus, like the cowpoxvirus, is an Orthopoxvirus. The original vaccine to prevent human smallpox was prepared.

Recombinant Poxviruses provides a comprehensive examination of poxviruses with an emphasis on the potential of these viruses as new vaccines.

Description Poxviruses (Current Topics in Microbiology & Immunology) EPUB

The book considers a wide range of issues involved in. Poxviridae is a family ofvertebrates, and arthropods serve as natural hosts. There are currently 83 species in this family, divided among 22 genera, which are divided into two subfamilies. Poxviruses are brick or oval-shaped viruses with large double-stranded DNA genomes.

Poxviruses exist throughout the world and cause disease in humans and many other types of animals. Poxvirus infections typically result in the formation of lesions, skin nodules, or disseminated rash. Poxviruses are large, brick-shaped or ovoid, linear double-stranded DNA ( kbp) containing core within a double membrane and a lipoprotein envelope carrying virions measuring approximately × nm (vaccinia virus) (Figures 11–1 and 11–2).The core is flanked by two lateral bodies containing several viral enzymes and proteins, including DNA-dependent RNA polymerase and.

Smallpox vaccine, Orthopoxvirus vaccinia, was used extensively for routine vaccination against variola virus. Historically poxvirus infections were laboratory confirmed by a combination of approaches including pock morphology on chicken embryo chorioallantoic membranes (CAMs), serologic reactivity, and electron microscopy (EM).

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Although EM can distinguish parapoxviruses from other poxviruses. This combination makes the book relevant for graduate students, researchers new to the field and to experienced poxvirologists.\/span>\"@ en\/a> ; \u00A0\u00A0\u00A0\n schema:description\/a> \" Genus orthopoxvirus: vaccinia virus \/ Geoffrey L.

Smith -- Genus othopoxvirus: monkeypox virus \/ Inger K. Damon -- Genus othopoxvirus: cowpox virus. Introduction. Welcome to my Pox Virus page. This website was constructed for a class at Stanford University called Human Biology Humans and Viruses, taught by Dr.

Robert here for links to web sites about other human virus families. The focus of this page is on small pox, which, from the beginning of history, caused devastating epidemics worldwide.

This chapter deals with poxviruses belonging to the family Poxviridae and subfamily Chordopoxvirinae. The G+C contents of orthopoxviruses, yatapoxviruses, Molluscum contagiosum virus (MCV), and parapoxviruses are ~33, ~32, ~60, and ~63%, respectively. The zoonotic poxviruses include members of the genera Orthopoxvirus (monkeypox virus, cowpox virus, and the vaccinia virus subspecies.

Poxviridae - Poxviruses: Genus: Viral Images: Example Virus Name: Image Description: Subfamily Chordopoxvirinae. Orthopoxvirus: Vaccinia: From Dr. Milan of. An illustration of an open book. Books. An illustration of two cells of a film strip. Video. An illustration of an audio speaker. Audio.

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Software. An illustration of two photographs. Recombinant poxviruses Item Preview remove-circle Share or Embed This Item. Poxviruses are a diverse group of large, complex double-stranded DNA viruses that replicate in the cytoplasm of the host cell.

From: Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases (Eighth Edition), Poxviruses parasitize invertebrates, birds, reptiles and mammals suggesting that the family Poxviridae is an ancient virus family. The genomes are linear and encode a large complement of genes.

Essential viral functions are clustered in the central region of the genome and a core group of critical genes are conserved among all poxviruses. Get this from a library. Poxviruses. [R W Moyer; P C Turner;] ISBN: OCLC Number: Purchase Viral Polymerases - 1st Edition.

Print Book & E-Book. ISBNBiology of Poxviruses. by Samuel Dales,B.G.T. Pogo. Virology Monographs Die Virusforschung in Einzeldarstellungen (Book 18) Thanks for Sharing. You submitted the following rating and review. We'll publish them on our site once we've reviewed : Springer Vienna.

Poxviruses 1. Poxviruses By: Lopez, Aileen P. Mundo, Argelyn M. Properties of Poxviruses Structure and composition Largest viruses dsDNA, kb Brick shaped “dumbbell” core (contains nucleic acid) Lateral bodies (unknown function) Enveloped Resistant to inactivation More than polypeptides Many target the immune response Replicate in cytoplasm Tend to be highly species.

Poxviruses are brick‐shaped, enveloped viruses, each containing a linear, double‐stranded DNA (deoxyribonucleic acid) genome of – kilobases (kb).

Several family members, including variola, monkeypox, cowpox, vaccinia, orf and molluscum contagiosum viruses, cause disease in humans. This volume, Biology of Poxviruses, marks our debut as editors of this well known series.

We plan to continue the tradition of providing a forum for exten­ sive, critical reviews of individual virus groups, as exemplified by the present volume. But the pace of discovery is accelerating so rapidly. Viruses belonging to the Poxvirus family (genus Orthopoxvirus) that can naturally infect humans and mammals include variola virus (smallpox), monkeypox virus, vaccinia virus, cowpox virus, buffalopox virus, camelpox virus, and cantagalo topic focuses on human disease associated with smallpox and monkeypox infection.

Smallpox was a serious, contagious, and often fatal infectious. Four genera of poxviruses may infect humans: orthopox, parapox, yatapox, molluscipox. Create a book Download as PDF Printable ia virus, used in smallpox vaccine genus Orthopoxvirus, family Poxviridae.

Inoculation with vaccine Dryvax or through direct contact. Poxviruses are large, enveloped viruses that replicate in the. Abstract. The poxviruses are distinguished principally by their unusual morphology, large DNA genome, and cytoplasmic site of replication. Smallpox, which is caused by variola virus, was recognized many centuries ago as a distinct disease entity because of its striking symptoms and high mortality.

(Ortho: from Greek orthos, “straight”). The genus Orthopoxvirus contains a number of species that can infect animals and most well known member of the genus is variola virus, the causative agent of smallpox.

Other notable members include vaccinia virus which is used in the current smallpox vaccine; cowpox virus, first introduced by Edward Jenner in the late 18th Century as. Most poxviruses were named after the animal from which they were originally isolated (e.g., cowpox and camelpox), but the main reservoirs for the viruses may be rodents or other species (TABLE ).

The one large Poxviridae family contains two subfamilies: Chordopoxvirinae, which infect vertebrates, and Entomopoxvirinae, which infect insect hosts.

INTRODUCTION. Poxviruses are currently classified into two subfamilies, the Chordopoxvirinae (ChPV) and the ChPV infect vertebrates, and the Entomopoxivirinae infect insects. Within the ChPV subfamily, there are nine genera currently recognized, with classification based initially on morphological and biological characteristics: Avipoxvirus, Capripoxvirus, Cervidpoxvirus.

Poxviridae. The Poxviridae has two subfamilies: Chordopoxvirinae, poxviruses of vertebrates, and Entomopoxvirinae, poxviruses of genome is a linear dsDNA molecule with of kb; it contains inverted terminal repeated sequences which are covalently cross-linked at the end.

The last endemic case of smallpox occurred intotal eradication was confirmed inand the official account of the disease and its eradication has appeared.

Consequently, smallpox is not discussed below. However, its importance should not be forgotten. It helped to shape history, and it made history by being the first disease to be controlled by immunization and the first to be.Acura Integra Electrcial Troubleshooting Manual Factory Book 87 Damaged Intellectual Property Unfair Competition And Publicity Convergences And Development European Intellectual Property Institutes Network Series.

#Now You Get PDF BOOK: Biology Of Poxviruses Virology Monographs. Please Share, Thank You#.Poxviruses of psittacine birds appear to represent a third, similarly diverged clade.

Divergence to this extent renders it extremely difficult to identify pan-genus oligonucleotide probes for PCR amplification and sequencing, and consequently existing phylogenetic information across the genus is limited to less than a handful of gene loci.